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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf0a59b18e769de6b65ad457b6f5d6826b7660bf4a416530705b4d4037a357d' 
  AND token = 'cxJO/tltRqWspEuxUSHDqGJS3drDv8q9P1/+4Z1ZL/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}