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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9c884ed44475c86e8d605b3ff914989e946756c1b8db6bdd81e8a96d815f781' 
  AND token = 'rGqnMuOoCR3Sg1GpItGiyFYcTDozDxq8iUKMCD7nITs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}