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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1fffbe8b2c74a230a32ca7e9cc3ddcec5c0591f167ee60950be95ff0d446c06' 
  AND token = '39XViAlJmXoPdtyJPKHkExn7JlpmhazStGcYWo6NK/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}