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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8a192b0495edb32ea66de722cd2310bba26a2e6c5f53d36afbe9db74679b14' 
  AND token = 'd8jum4gA0AKHWRWc4Q1cTk3GRSjmOv2XaqiBMf8NpeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}