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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ec6ef225e946f462efc13065ffac2d98e66077e2e140fe97f662af7f63883c3' 
  AND token = 'C/xHQEgtc9Dhfw15O8F5zSVJYNmW7zFrnt4fHY14GKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}