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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753b42dc0005713efcf07d1afad496a11d29da7ec73f3f0c8664d6fb3e039f5f' 
  AND token = 'vfycSL7TnJCAwHW7fZThdbIwp7l8WFhS8ukkC6Da9Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}