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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4d49902cfe616b7f480c6db1f27c1aaee68e5933af6df07e18884d65087b3b1' 
  AND token = '33OvKXzo22LUJ09Wdpxl6zzvSZj9zqOS6p78EgLTnvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}