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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e7e957f6097b6638b2c7af4cf5c8a2bf33779afef1b023ae10ec4e43bcac64f' 
  AND token = '3NQkAfQBWw4Y1k2LNSdUcQKvb3gIupfT9FdZcmH3gpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}