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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eb17dede7eb27b7a10b8fd830186abdd339e750cb41dc45b8e69664a4b60845' 
  AND token = 'aI+5Oe54JSISgIh7xgzSEiB1yWsOdvSzQwliddEJozM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}