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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '863b2e16b76524a68b00089abddffa08067c78ebf3b7cf68220b9bcf6dac45e3' 
  AND token = 'EewYEwqQWd/56r91a+wFCeqc/umgmnqrMjdVQ7xY13I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}