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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7780db272e72ad7624c0532a6f94fb7afa5777a07c2d1bcfc13c0ce74c989283' 
  AND token = '6akmT9abQXg509+H/E6/MSywtjGWhFtbOF3GOy35Wm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}