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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b90061910226492edab20720df76dd5fd4e240fcf1a5a72e6be0841e678c11' 
  AND token = 'X7IP61QxUVI6NLx6DJ1xcWxIDeMLZK5aCXAt/fQAAf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}