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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19271f20977c638ba2d8c686bca3f1d553a15015e7588ce91aa395e86df16c5c' 
  AND token = 'ic8nzPKnic/nsnZ1coyUE1JYSQ9H91mV9POq/P+4Vog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}