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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa82c060d926b48ccf976acb2ea9cb622f75f78f8a6fe5bc98ee3e5f300b05a' 
  AND token = 'AvoL4mLGOMK9J0lBJguL3zMC4Zy3MlgdL36pkGVukc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}