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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65574622cbdf981c1cd25eb13352f974a86b9deb0c727840503d00466e3e2af0' 
  AND token = 'qj1pojr8uSQEemwdRhQrVC3ezJ0ZhdjfdQYcz9YF+EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}