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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44613e932b63597a71cf1ef1a1428075e55b00226328a2a18a67fd8bd922e0fd' 
  AND token = 'T8H1uuLKCkWmWjiPW4IlbtpOErSM0r87ZrPm2C2WFqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}