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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed69e4e3dfd2968029bf5c8b2bf2595fa61a24adfc0c8c4640c7e1dcb0de8356' 
  AND token = '+cVY/rNyEmpmmTgOn0Olp5R1ASdjO6Q+vbJN7McKlx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}