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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cb2db8f34bed690352073cefabf4fa143ae77307f186668d8240948905a4eeb' 
  AND token = 'Te2e1jGidDSvNDX/PYDO8EgnmyXCFV4BWkNKbSDl1mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}