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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0372a315b2ebd1f06fb3d4387b1c68df492e0fc5fa8ee0b4aa05fa60482259' 
  AND token = '3VXvL2odvl/0vNXVK6GQeEcc3+0PtXacK/7BS5n/JMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}