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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f446e17906d79469bed608072cb0a04f6352a843c9558d3f6d822d0d44ea477d' 
  AND token = 'dp5fH1Iv/26zyrSuXZ+0/fBwr2DD+0OiP/LPiGMO+8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}