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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a6b3d75e414c37ab154d1ee0f87cb30457f06b0e6a4ab7760ac715f933496b' 
  AND token = '6A+ukCBwe/NjoQMTr6Pa4EZEPjpD+TCYLZA9Llu+StU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}