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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60918f50a603c21ae506592cbf4ca44fea707ecd17907b9f46e9e1b1b60cb9f9' 
  AND token = '4lSgeH5MDM07SmENvslCTqtSqdEk2axF/gfYRdZNy38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}