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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb1dc2ee0887e0081f6bca70b38971af6835c9dcaa32424f88d728c48e657a4d' 
  AND token = 'LwOF+Kxg6aSifDhfHa6ZZpyzTY+eWMWf+DR7BSKZRpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}