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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734739834b63c58b2cadd6eeac7131522c6e0f097fc2750803ed46faf3017776' 
  AND token = 'VPEDuPl3GResQ9/EtKvDG/BXBnKBf7TId3T07BQ58sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}