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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72502b0388fa536597b6b0fb7858d1cdb506275432cbdfafa5cbc9023bdcb6d' 
  AND token = 'Ye2mZbUwD6b9h/Je2EK8MF7+nlT71XSFf+QainPr8Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}