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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6d90213559d5a529cc49bf337096ea6333599f4bd1c8dac77b7317bbfb0f99' 
  AND token = 'NmtenJnhUQqmtW2JBy7BWas/9d5Ty0Wwt2Mtx2CKHwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}