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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a339baa8eb59219b2c35f299512f781691f8ddc80f355807ef154ee5c35f4f4' 
  AND token = 'rdBs4lc3iRn55x1bTZ/PEltUTyIPn8Zt1VHGJPMRtws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}