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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d565e35ff12f6ba93e7189b1a6dd8f7856c93e50680f0715bb45f686cc11e6a' 
  AND token = 'Vm3No/mlhz04JSf6/pzhJmAmi0mNc6Yqh/2AVdiA7jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}