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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8f036769f208f250926aed6f50b0596bcc17003e4a36065bf3860ce470c55c' 
  AND token = 'c0/kchwHHrmuaZP8tVEqDiGdEC8qw58kgO5Q7ag8bd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}