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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f17c4b3422e7f1ffbca15e30fe1388434a49cb1633ea3875f869cb0cea4020d9' 
  AND token = 'seb2EOJrl6k5mgmIF2ZsaNIvnsw3EWGlOhwTKRzHwdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}