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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c025f74213749f557e0e9a758b043d8cda11671a2f54c0590bd80e23f40af5a' 
  AND token = 'O5U+C0H5XEWS0afqWdaeM9VQdF4HYCDLCfehg+PDtOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}