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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6911c8e06d66a14351dafd9be113faf6187bdf820aa29677f167197d6570eb45' 
  AND token = 'HonFr9FlSIjlUM77BmvcU8WQgLKPXSOf/0QdHbd2Sdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}