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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df0ec57c84dbdfb0115038bb03d5477a95883076979ce41644eed5615dc4f49d' 
  AND token = '2hTyz7N2hWdKR5CiH2N3HGwdXPdZ3oaZkVCFVA/fjaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}