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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f64afed6d914750e5d4366444c14661533175b7152b8b40ecb0b9cfef8923fb4' 
  AND token = '5i2on5BCXuwLp56FWDQv4qE+rWblvAQSjTPwR3GRgm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}