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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782bd88016b35c9c40ca98387be30d233ec46ce15bc628a1052c58d25a5f3342' 
  AND token = '4A6OlVavaZKWpwzHd++sQFd3HkeXshcqZZD5qkB68ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}