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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00923e7c6415807e52ab1d62df565a8658e910f1856131e57310cd08f0d2c277' 
  AND token = 'ntV/6pn0Pj5n5Rga1zY8odbyH67kiKkYI3mxJVArcFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}