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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50c15b755339eb48031b25ae3b2cbdbc529407cb5d3d9fbe9dc138253df544a' 
  AND token = 'TzyVWxusv6CAVxo05U3aH0Y8eNcK3VLQk77H0l/vkos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}