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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5ad9f977f9cf45496199066dfcd91964019e5e641dd83f872db260b4c20d344' 
  AND token = '5lSXYJHDCmIHk6WsHfJBXYbJxS3nR/tHNs4V1MzL6WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}