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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278dee258f28bd3f97397a838ee7acc7b6f59468933ee7c1b3dcb83b25dfd157' 
  AND token = 'u628ygiLqXnfkVdKHT6Des6mBln4Wt95bmrfuMfUYIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}