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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a04176ee92c419511d1123673fd67c6831f1c2a6e8566443733d41e3641d7d' 
  AND token = 'DXanfUspaJ14Bkh8e8wxKkBA3Y/GMix5vLJQT6U3JUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}