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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5dbe4a5f97f08e5238ab9230fa88fb3c77896515d2f31d4e21bbd2fffe8e0b5' 
  AND token = 'UR+XQ032gDsXTIyeWDvHtmUE6oPymtTyx2XlTXtJEAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}