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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03744b2b6ce7f3076fb788ab0e56cda93aded8bd1d25e2810d164601cca87cab' 
  AND token = 'dpEuPY+tFzwxtBdQGRrk2d5if1VcVpto8UJ2d1tbb8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}