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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51eac32d6c1e52c683e828a10d1628be7685f9b31eaf12f9f031ec9c5e753949' 
  AND token = 'dYAlxXalxouWyMFSM5IbDgY3f6CQpkUXoip1plyS2EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}