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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48131a521816ed99e7f0f9c9f99dd23518dede33f0b56142c32e40f1140b9c2c' 
  AND token = 'AU1oxLJ6xDolcNmI6zVV2BoKD3CyCrxQ+QOBs/JOTgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}