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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38c34cf201074973f48639f8924e9c995a1c9e46c7a0a06e3355b5c6882aa7f4' 
  AND token = 'gYBW+Dtgg/cGQ0ytlJrsc7yIxm/vg7RG7RrTJfPS49k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}