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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfccfd56d63799008f722025f7a89fe0fe2c72fd4202211d7686762ae9d23b04' 
  AND token = 'G04FMfWbwBUl8MdgDxPPKHUWkw64NqwF/ei9TMjhxjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}