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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c9b1bc4b06745159d067b15f69b9dedf66e9d51abac1381a7f91e7f18d02c9' 
  AND token = '+itsnGaEZgBJoEpeZ12y4qQqKLEE/74YLDE7G8keioQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}