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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '574ce7fe60e449f21d4ea631350488a3127f0722f8634a87ed9d090bf025dce1' 
  AND token = 'IGEA2tXwYW540eUJdXEzF/0j/zzyWRWZkwBt55fnSGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}