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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a99b89e656f4fb4e5a6a60d79bc3925df3b3e5c1f135c3f413815f9d823aee' 
  AND token = 'lAK5X3E+h284HZ9/qZG6sw/WyrCsti+ji0memsaz8yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}