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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ec84a51d987a67e499f3ee8426bd7998f421b209cae0db532c0f40768cf5b0' 
  AND token = 'JINa43F8CanXXrVTeMxd5Jaf9F5e/DyWcWFXT+KEdHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}